Studies on 3-Methoxyproline and 3-Hydroxyproline
نویسندگان
چکیده
منابع مشابه
Studies on 3-methoxyproline and 3-hydroxyproline.
The cis and trans racemates of synthetic 3-hydroxyproline and of synthetic 3-methoxyproline were interconverted by an epimerization reaction at carbon atom 2. The interconversions are proof of the diastereomeric nature of the synthetic isomers. Assignments of cis and trans configuration were made from nuclear magnetic resonance studies. Synthetic cisand trans-3-hydroxy-DL-proline were partially...
متن کامل3-Hydroxyproline content of normal urine.
Values for total 3-hydroxyproline and 4-hydroxyproline were obtained from 24-h urine specimens of 18 healthy human subjects of both sexes, whose ages ranged from the first to the sixth decade in age. Urinary 3-hydroxyproline levels, not earlier described to our knowledge, were determined by an isotope-dilution method requiring considerable purification and utilizing the amino acid analyzer for ...
متن کاملEffect of 3-hydroxyproline residues on collagen stability.
Collagen is an integral part of many types of connective tissue in animals, especially skin, bones, cartilage, and basement membranes. A fibrous protein, collagen has a triple-helical structure, which is comprised of strands with a repeating Xaa-Yaa-Gly sequence. l-Proline (Pro) and 4(R)-hydroxy-l-proline (4-Hyp) residues occur most often in the Xaa and Yaa positions. The 4-Hyp residue is known...
متن کاملAnimal Studies on Spacelab - 3
The flight of two squirrel monkeys and 24 rats on Spacelab-3 wall the first mission to provide "hands-on" maintenance of animals in a laboratory environment. With few exceptions, the animals grew and behaved normally, were free of chronic str-ass, and d:tffered from ground controls only for gravity-dependent parameters. One of the monkeys exilibited symptoms of space sickness similar to those o...
متن کاملStudies on purified 3-hydroxyanthranilic acid oxidase.
3-Hydroxyanthranilic acid oxidase is known to cat,alyze the oxidation of 3-hydroxyanthranilic acid to a very unstable aliphatic compound, which may either be spontaneously transformed into quinolinic acid or undergo enzymic conversion to picolinic or nicotinic acid, or both (l-3). According to Mason (4), this enzyme has been classified as an “oxygen transferase,” since the oxygen consumed, 1 mo...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1966
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)96774-8